Alert

topiramate

Pronunciation: toe PYRE a mate

Brand: Qudexy XR Sprinkle, Topamax, Topamax Sprinkle, Trokendi XR

Topiramate Sprinkle

slide 1 of 41, Topiramate Sprinkle,

15 mg, capsule, white, imprinted with TEVA, 7335

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Topiramate Sprinkle

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25 mg, capsule, white, imprinted with TEVA, 7336

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Topiramate

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25 mg, round, white, imprinted with IG, 278

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Topiramate

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50 mg, round, yellow, imprinted with IG, 279

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Topiramate

slide 5 of 41, Topiramate,

100 mg, round, yellow, imprinted with IG, 280

Image of Topiramate
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Topiramate

slide 6 of 41, Topiramate,

200 mg, round, pink, imprinted with IG, 281

Image of Topiramate
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Topamax

slide 7 of 41, Topamax,

25 mg, round, yellow, imprinted with OMN, 25

Image of Topamax
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Topamax

slide 8 of 41, Topamax,

50 mg, round, yellow, imprinted with OMN, 50

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Topamax

slide 9 of 41, Topamax,

100 mg, round, yellow, imprinted with OMN, 100

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Topamax

slide 10 of 41, Topamax,

200 mg, round, orange, imprinted with OMN, 200

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Topamax Sprinkle

slide 11 of 41, Topamax Sprinkle,

25 mg, capsule, white, imprinted with TOP, 25 mg

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Topamax Sprinkle

slide 12 of 41, Topamax Sprinkle,

15 mg, capsule, white, imprinted with TOP, 15 mg

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Topiramate

slide 13 of 41, Topiramate,

25 mg, round, white, imprinted with IG, 278

Image of Topiramate
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Topiramate

slide 14 of 41, Topiramate,

50 mg, round, yellow, imprinted with IG, 279

Image of Topiramate
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Topiramate

slide 15 of 41, Topiramate,

100 mg, round, yellow, imprinted with IG, 280

Image of Topiramate
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Topiramate

slide 16 of 41, Topiramate,

200 mg, round, pink, imprinted with IG, 281

Image of Topiramate
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Topiramate

slide 17 of 41, Topiramate,

100 mg, round, yellow, imprinted with S, 711

Image of Topiramate
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Topiramate

slide 18 of 41, Topiramate,

200 mg, round, brown, imprinted with S, 712

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Topiramate Sprinkle

slide 19 of 41, Topiramate Sprinkle,

25 mg, capsule, white, imprinted with ZA 64, 25mg

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Topiramate

slide 20 of 41, Topiramate,

50 mg, round, white, imprinted with ZD15

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Topiramate

slide 21 of 41, Topiramate,

50 mg, round, yellow, imprinted with G, 50

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Topiramate

slide 22 of 41, Topiramate,

25 mg, round, white, imprinted with 122, C

Image of Topiramate
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Topamax

slide 23 of 41, Topamax,

100 mg, round, yellow, imprinted with TOPAMAX, 100

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Topamax

slide 24 of 41, Topamax,

200 mg, round, peach, imprinted with TOPAMAX, 200

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Topamax

slide 25 of 41, Topamax,

25 mg, round, white, imprinted with TOP, 25

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Topiramate

slide 26 of 41, Topiramate,

100 mg, round, orange, imprinted with 124, Cipla

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Topiramate

slide 27 of 41, Topiramate,

100 mg, round, yellow, imprinted with APO, TP 100

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Topiramate

slide 28 of 41, Topiramate,

100 mg, oblong, yellow, imprinted with 93, 7219

Image of Topiramate
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Topiramate

slide 29 of 41, Topiramate,

200 mg, capsule, pink, imprinted with 125, Cipla

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Topiramate

slide 30 of 41, Topiramate,

200 mg, round, pink, imprinted with APO, TP 200

Image of Topiramate
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Topiramate

slide 31 of 41, Topiramate,

200 mg, oblong, pink, imprinted with 93, 7220

Image of Topiramate
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Topiramate

slide 32 of 41, Topiramate,

25 mg, round, white, imprinted with APO, TP 25

Image of Topiramate
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Topiramate

slide 33 of 41, Topiramate,

25 mg, oblong, white, imprinted with 93, 155

Image of Topiramate
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Topiramate

slide 34 of 41, Topiramate,

50 mg, round, orange, imprinted with 123, C

Image of Topiramate
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Topiramate

slide 35 of 41, Topiramate,

50 mg, round, white, imprinted with APO, TP 50

Image of Topiramate
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Topiramate

slide 36 of 41, Topiramate,

50 mg, oblong, yellow, imprinted with 93, 7540

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Topiramate ER

slide 37 of 41, Topiramate ER,

100 mg, capsule, brown/gray, imprinted with UPSHER-SMITH, 100 mg

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Topiramate ER

slide 38 of 41, Topiramate ER,

150 mg, capsule, gray/yellow, imprinted with UPSHER-SMITH, 150 mg

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Topiramate ER

slide 39 of 41, Topiramate ER,

200 mg, capsule, brown/gray, imprinted with UPSHER-SMITH, 200 mg

Image of Topiramate ER
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Topiramate ER

slide 40 of 41, Topiramate ER,

25 mg, capsule, gray/pink, imprinted with UPSHER-SMITH, 25 mg

Image of Topiramate ER
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Topiramate ER

slide 41 of 41, Topiramate ER,

50 mg, capsule, gray/yellow, imprinted with UPSHER-SMITH, 50 mg

Image of Topiramate ER
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What is the most important information I should know about topiramate?

Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision.

Topiramate may harm an unborn baby. There may be other seizure medicine that can be more safely used during pregnancy. Tell your doctor right away if you become pregnant.

Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration. Tell your doctor if you have decreased sweating, high fever, and hot dry skin.

Topiramate can also increase the level of acid in your blood (metabolic acidosis). Tell your doctor if you have irregular heartbeats, shortness of breath, loss of appetite, or trouble thinking.

Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not stop using topiramate suddenly or you could have increased seizures.

What is topiramate?

Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old.

Some brands of topiramate are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun.

Topiramate may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking topiramate?

You should not use topiramate if you are allergic to it. Do not take Trokendi XR within 6 hours before or 6 hours after drinking alcohol.

Tell your doctor if you are sick with diarrhea, or if you have ever had:

  • glaucoma or other eye problems;
  • metabolic acidosis (high levels of acid in your blood);
  • kidney disease, kidney stones, or dialysis;
  • lung disease, breathing problems;
  • mood problems, depression, or suicidal thoughts or actions;
  • liver disease;
  • a growth disorder; or
  • soft or brittle bones (osteoporosis, osteomalacia).

Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby. You may need blood tests to make sure you do not have metabolic acidosis, especially if you are pregnant.

Some people have thoughts about suicide while taking an anticonvulsant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Do not start or stop taking topiramate during pregnancy without your doctor's advice. Topiramate may increase the risk of low birth weight and cleft lip and/or cleft palate in a newborn. There may be other seizure medicine that can be more safely used during pregnancy. Tell your doctor right away if you become pregnant.

Topiramate can make birth control pills less effective. Use a barrier form of birth control (such as a condom or diaphragm with spermicide) to prevent pregnancy while taking topiramate.

It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.

How should I take topiramate?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Topiramate can be taken with or without food.

Swallow the tablet whole and do not crush, chew, or break it. The Trokendi XR extended-release capsule must be swallowed whole. Do not break or open.

If you cannot swallow a Qudexy XR or Topamax Sprinkle Capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or other soft food. Swallow the mixture right away without chewing. Do not save it for later use.

Carefully follow the swallowing instructions for your medicine.

Topiramate doses are sometimes based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Drink plenty of liquids while you are taking topiramate, to prevent kidney stones or an electrolyte imbalance.

You will need frequent medical tests. If you need surgery, tell the surgeon ahead of time that you are using topiramate. Any medical care provider who treats you should know that you take seizure medication.

Do not stop using topiramate suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

Call your doctor if your seizures get worse or you have them more often while taking topiramate.

Store at cool room temperature away from moisture, light, and high heat.

What happens if I miss a dose?

Take the medicine as soon as you can. Do not take two doses at one time. Skip a missed Topamax dose if your next dose is due in less than 6 hours.

Call your doctor if you have missed more than one dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of topiramate can be fatal. Overdose can cause drowsiness, agitation, depression, double vision, thinking problems, problems with speech or coordination, fainting, and seizure (convulsions).

What should I avoid while taking topiramate?

Do not drink alcohol. Dangerous side effects or increased seizures may occur.

Avoid becoming overheated or dehydrated in hot weather. Topiramate can increase body temperature and decrease sweating, leading to life-threatening dehydration (especially in children).

Avoid the use of a ketogenic or "ketosis" diet (high in fat, low in carbohydrates) while you are taking topiramate.

Topiramate may cause blurred vision or impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.

Also avoid activities that could be dangerous if you have an unexpected seizure, such as swimming or climbing in high places.

What are the possible side effects of topiramate?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening mood symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • vision problems, blurred vision, eye pain or redness, sudden vision loss (can be permanent if not treated quickly);
  • confusion, problems with thinking or memory, trouble concentrating, problems with speech;
  • dehydration symptoms --decreased sweating, high fever, hot and dry skin;
  • signs of a kidney stone --severe pain in your side or lower back, painful or difficult urination;
  • signs of too much acid in your blood --irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath; or
  • signs of too much ammonia in your blood --vomiting, unexplained weakness, feeling like you might pass out.

Common side effects may include:

  • dizziness, drowsiness, tired feeling, slow reactions;
  • problems with speech or memory;
  • abnormal vision;
  • numbness or tingling in your arms and legs, decreased sensation (especially in the skin);
  • changes in your sense of taste;
  • feeling nervous;
  • nausea, diarrhea, stomach pain, loss of appetite;
  • fever, weight loss; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect topiramate?

Using topiramate with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression.

Tell your doctor about all your other medicines, especially:

  • acetazolamide;
  • zonisamide;
  • divalproex, valproic acid; or
  • birth control pills.

This list is not complete. Other drugs may affect topiramate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about topiramate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 18.01. Revision date: 5/9/2019.

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