Alert

adenosine

Pronunciation: a DEN oh seen

Brand: Adenocard, Adenoscan

What is the most important information I should know about adenosine?

Before receiving adenosine, tell your doctor if you have asthma or other breathing problems, or if you have ever had a seizure.

What is adenosine?

Adenosine is a naturally occurring substance that relaxes and dilates blood vessels. Adenosine also affects the electrical activity of the heart.

Adenosine is used to help restore normal heartbeats in people with certain heart rhythm disorders.

Adenosine is also used during a stress test of the heart.

Adenosine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving adenosine?

You should not be treated with adenosine if you have a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker), or slow heartbeats that have caused you to faint.

Your doctor will perform tests to make sure you do not have conditions that would prevent you from safely receiving this medicine.

Tell your doctor if you have ever had:

  • asthma, COPD, bronchitis, emphysema, or other breathing problems;
  • seizures; or
  • angina (chest pain).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

Tell your doctor if you are breast-feeding. You may need to stop nursing for a short time after you receive adenosine.

How is adenosine given?

Before your heart stress test: Avoid coffee, tea, cola, chocolate, energy drinks or other sources of caffeine. They can interfere with the results of your test.

Adenosine is given as an infusion into a vein. A healthcare provider will give you this injection.

You may receive only one dose of this medicine. Repeat doses may be given if needed to restore normal heartbeats.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.

Your heart rate will be constantly monitored using an electrocardiograph or ECG (sometimes called an EKG). This will help your doctor determine how long to treat you with adenosine.

What happens if I miss a dose?

Adenosine is usually given as a single dose in a medical setting and does not have a daily dosing schedule.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving adenosine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of adenosine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • severe shortness of breath;
  • chest pain or tightness, pain spreading to your jaw or shoulder;
  • fluttering in your chest;
  • a light-headed feeling, like you might pass out;
  • a seizure;
  • severe headache, blurred vision, pounding in your neck or ears; or
  • sudden numbness or weakness, problems with vision or speech.

Common side effects may include:

  • flushing (sudden warmth, redness, or tingly feeling);
  • chest pressure, shortness of breath;
  • nausea;
  • headache, dizziness; or
  • discomfort in your neck or jaw.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect adenosine?

Tell your doctor about all your other medicines, especially:

  • aminophylline;
  • digoxin;
  • dipyridamole;
  • theophylline; or
  • verapamil.

This list is not complete. Other drugs may affect adenosine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about adenosine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 1.01. Revision date: 9/25/2018.

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